# Four Faces of Infective Endocarditis: Where Thinking Outside the Box Was Crucial

**Authors:** Ali El-Shamy, Patrick Man, Gayatri Vijapurkar, Baher Hanna, Attila Kardos

PMC · DOI: 10.3390/jcm14072162 · 2025-03-22

## TL;DR

This paper discusses four complex cases of infective endocarditis and emphasizes the need for a multidisciplinary team approach in diagnosis and treatment.

## Contribution

The paper introduces the concept of an Extended Endocarditis Team for managing complex IE cases.

## Key findings

- The incidence of infective endocarditis has increased with advances in cardiac treatment technologies.
- A multi-disciplinary approach is recommended for prompt diagnosis and treatment decisions.
- Four complex IE cases are presented to highlight management challenges.

## Abstract

Background/Objectives: Infective Endocarditis (IE) presents both a challenging diagnostic and treatment task. Methods: The incidence of IE has grown with the advancement in treatment technologies offered to patients, including intra-cardiac electrical device insertion and a variety of transcutaneous structural interventions. Results: Guidelines recommend the involvement of a multi-disciplinary approach to prompt diagnosis and decisions regarding treatment. Conclusions: We present the management conundrums of four complex cases of IE and highlight the importance of the Extended Endocarditis Team.

## Linked entities

- **Diseases:** Infective Endocarditis (MONDO:0000565)

## Full-text entities

- **Diseases:** Endocarditis (MESH:D004696)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

15 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11989933/full.md

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Source: https://tomesphere.com/paper/PMC11989933