# Long-Term Outcomes of Surgical and Transcatheter Interventions for Tricuspid Regurgitation: A Comprehensive Review

**Authors:** Vasiliki Tasouli-Drakou, Ibrahim Youssef, Arsalan Siddiqui, Tahir Tak

PMC · DOI: 10.3390/jcm14072451 · 2025-04-03

## TL;DR

This review examines long-term results of surgical and transcatheter treatments for tricuspid regurgitation to help guide clinical decisions.

## Contribution

The paper provides a comprehensive review of recent clinical studies on long-term outcomes of TR interventions.

## Key findings

- There is limited evidence on long-term outcomes of TR interventions.
- Recent advancements in surgical and transcatheter treatments have improved short-term outcomes.
- The review aims to guide clinicians in choosing optimal treatment strategies for TR patients.

## Abstract

Impacting more than 70 million people worldwide, tricuspid regurgitation (TR) refers to the retrograde flow of blood from the right ventricle to the right atrium due to the improper closure of the tricuspid valve. Depending on the severity of TR, signs and symptoms can range from asymptomatic to features of right heart failure, including dyspnea, exercise intolerance, peripheral edema, and ascites. Severe features such as these necessitate treatment. In recent years, advancements in management, including surgical and transcatheter interventions, have taken prominence, leading to improved short-term outcomes in this patient population. However, there is still a dearth of evidence regarding the long-term outcomes of surgical and transcatheter interventions for TR. This comprehensive review aims to present clinicians with recent findings from pivotal clinical studies on interventional clinical outcomes in an effort to help guide their judgment when it comes to deciding the best course of treatment for their patients.

## Full-text entities

- **Diseases:** right heart failure (MESH:D006333), ascites (MESH:D001201), dyspnea (MESH:D004417), edema (MESH:D004487), TR (MESH:D014262)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11989269/full.md

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Source: https://tomesphere.com/paper/PMC11989269