# The Role of Endoscopy in the Postoperative Management of Patients Treated for Esophageal Atresia: 20 Years of Experience

**Authors:** Francesco Grasso, Fabio Baldanza, Sara Pernicone, Marco Pensabene, Maria Sergio, Maria Rita Di Pace

PMC · DOI: 10.3390/diagnostics15070843 · Diagnostics · 2025-03-25

## TL;DR

This study shows that endoscopy is a safe and effective method for detecting and treating complications in infants after surgery for esophageal atresia.

## Contribution

The study emphasizes the importance of early endoscopic evaluation in routine follow-up care for patients treated for esophageal atresia.

## Key findings

- Endoscopic evaluations detected complications in 27% of patients, including anastomotic strictures and reflux esophagitis.
- Endoscopic dilatations for stenosis were successful, with an average of three procedures per patient.
- 91% of patients had normal growth parameters by the first year of life.

## Abstract

Background/Objectives: Endoscopy plays a well know role in managing patients treated for esophageal atresia (EA), allowing the detection and treatment of complications such as anastomotic strictures, gastroesophageal reflux disease, and other structural abnormalities, during the critical first year of life. Nevertheless, we would like to underline the importance of endoscopy early in the follow-up of patients treated for EA, as recommended by guidelines. This study evaluates the role of endoscopy in managing patients treated for esophageal atresia (EA), focusing on the detection and treatment of complications such as anastomotic strictures, gastroesophageal reflux disease, and other structural abnormalities during the critical first year of life. Methods: A retrospective analysis was conducted over 20 years at our institution. Clinical assessments were performed at 3, 6, and 9 months to monitor growth, feeding tolerance, and proton pump inhibitor (PPI) adjustments. Endoscopic evaluations were conducted under general anesthesia around one year of age. Results: Between 2003 and 2023, 84 patients underwent surgical treatment for EA, with complete follow-up data available for 77 patients. Complications occurred in 21 patients (27%), including 4 patients (5.5%) with isolated anastomotic stricture, 8 patients (10%) with reflux esophagitis, 8 patients (10%) affected by both stenosis and reflux, and 1 case (1.5%) of fistula recurrence. Endoscopic dilatations for stenosis were successful, averaging three procedures per patient. Growth parameters were normal in 91% of cases by the first year. Conclusions: Esophagogastroscopy is a safe and effective tool for diagnosing and managing complications after EA repair in infants. The minimally invasive procedure could allow early detection of esophagitis and strictures, offering significant therapeutic benefits. Given these important results, we would like to recommend its use in routine follow-up care.

## Linked entities

- **Diseases:** esophageal atresia (MONDO:0001044), gastroesophageal reflux disease (MONDO:0007186)

## Full-text entities

- **Diseases:** anastomotic stricture (MESH:D003251), esophagitis (MESH:D004941), EA (MESH:D004933), gastroesophageal reflux disease (MESH:D005764), fistula (MESH:D005402)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11989119/full.md

## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC11989119/full.md

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Source: https://tomesphere.com/paper/PMC11989119