# Rare Pulmonary Granular Cell Tumor Presenting as an Endobronchial Lesion: A Case Report

**Authors:** Abolfazl Sodagar, Sujeirys Paulino, Nismat Javed, Marcos Molina, Misbahuddin Khaja

PMC · DOI: 10.7759/cureus.80471 · Cureus · 2025-03-12

## TL;DR

A rare case of pulmonary granular cell tumor in a 33-year-old woman presented as an endobronchial lesion and resolved with conservative treatment.

## Contribution

This case report highlights the diagnostic challenges and management of a rare endobronchial granular cell tumor.

## Key findings

- pGCTs are rare and often mimic other endobronchial lesions, making diagnosis difficult.
- Conservative management can be effective for small, asymptomatic pGCTs.
- Bronchoscopy and biopsy are essential for accurate diagnosis and management.

## Abstract

Granular cell tumors (GCTs) are rare soft tissue tumors with a myogenic origin. While GCTs typically arise in the tongue, skin, and subcutaneous tissues, pulmonary involvement (pGCT) remains rare. The most common site in the case of pGCT is the bronchus, followed by the trachea and lung parenchyma. In this case, we discuss the presentation of a 33-year-old female with respiratory distress who was subsequently diagnosed with pGCT, and her dyspnea resolved after conservative management. Bronchoscopic evaluation and biopsy with histopathological examination remain the cornerstone for diagnosis and management. While most pGCTs are benign, a few can be malignant and require additional techniques for management. Given their infrequency, pGCTs can pose diagnostic challenges, often mimicking other endobronchial lesions clinically and radiologically. Management strategies range from conservative observation especially for smaller, asymptomatic tumors to surgical resection or bronchoscopic excision for those exhibiting significant symptoms, airway compromise, or features suggestive of malignancy.

## Linked entities

- **Diseases:** granular cell tumor (MONDO:0006235)

## Full-text entities

- **Diseases:** GCTs (MESH:D016586), dyspnea (MESH:D004417), respiratory distress (MESH:D012128), malignancy (MESH:D009369), soft tissue tumors (MESH:D012983), pulmonary (MESH:D008171)

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11988283/full.md

## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC11988283/full.md

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Source: https://tomesphere.com/paper/PMC11988283