# Research Progress of Neutrophil Extracellular Traps in Lung Cancer

## TL;DR

Neutrophil extracellular traps (NETs) play a key role in lung cancer progression and may offer new treatment strategies.

## Contribution

This paper reviews recent advances in understanding the role of NETs in lung cancer and their potential as therapeutic targets.

## Key findings

- NETs influence tumor microenvironment dynamics in lung cancer.
- NETs exhibit complex immune regulatory features in lung cancer progression.
- Targeting NETs may provide new therapeutic approaches for lung cancer treatment.

## Abstract

中性粒细胞胞外诱捕网（neutrophil extracellular traps, NETs）作为中性粒细胞活化后释放的网状复合结构，在恶性肿瘤病理进程中发挥关键调控作用。肺癌是全球范围内最常见的恶性肿瘤之一，发病率和死亡率均居高不下。近年研究发现，NETs通过其独特的病理机制参与肿瘤微环境动态调控，在肺癌演进过程中呈现出复杂的免疫调节特征，这一发现已逐渐成为肿瘤免疫学研究的热点领域。本文系统地梳理了NETs在肺癌领域的最新研究进展，深度剖析了NETs对肺癌发生发展的影响和在肺癌诊断中的潜在价值，以及靶向NETs防治肺癌的研究现状，旨在为提高肺癌患者治疗疗效和改善预后提供新的思路。

Inhibitors and drugs targeting NETs in lung cancer