# Closed genome sequence of Fretibacterium fastidiosum, a potential contributor to periodontal disease

**Authors:** Asuka Mori, Mashu Kudoh, Masae Kuboniwa, Christian Rückert-Reed, Tobias Busche, Marion Eisenhut, Eiichiro Fukusaki, Andrea Bräutigam, Bianca Laker

PMC · DOI: 10.1128/mra.00004-25 · Microbiology Resource Announcements · 2025-03-06

## TL;DR

This paper presents the complete genome sequence of Fretibacterium fastidiosum, a newly identified oral bacterium linked to periodontal disease.

## Contribution

The study provides the first closed genome sequence of Fretibacterium fastidiosum, enabling further research into its role in oral health.

## Key findings

- The closed genome sequence of Fretibacterium fastidiosum was successfully obtained.
- This bacterium is a recently identified member of the human oral microbiome.
- The genome data may help understand its potential contribution to periodontal disease.

## Abstract

Human oral microbiome consists of diverse bacteria. Not all oral bacteria are well characterized due to challenges in cultivation in vitro. In this study, we report the closed genome sequence of one of the recently identified oral bacteria, Fretibacterium fastidiosum.

## Linked entities

- **Diseases:** periodontal disease (MONDO:0002635)
- **Species:** Fretibacterium fastidiosum (taxon 651822)

## Full-text entities

- **Diseases:** periodontal disease (MESH:D010510)
- **Species:** Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Fretibacterium fastidiosum (species) [taxon 651822], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

19 references — full list in the complete paper: https://tomesphere.com/paper/PMC11984142/full.md

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Source: https://tomesphere.com/paper/PMC11984142