# Mesenteric Panniculitis in a Renal Transplant Patient With Systemic Lupus Erythematosus

**Authors:** Elizabeth Geyer-Roberts, Julia Grote, Andrew Banuelos

PMC · DOI: 10.7759/cureus.80340 · Cureus · 2025-03-10

## TL;DR

A 34-year-old woman with lupus developed a rare condition called mesenteric panniculitis, suggesting a possible link between autoimmune diseases and this condition.

## Contribution

This case report explores a potential connection between systemic lupus erythematosus and mesenteric panniculitis.

## Key findings

- The patient had a lupus flare and changes in immunosuppressive therapy before MP diagnosis.
- MP was identified through imaging and is considered rare and of unknown cause.
- The case suggests a possible autoimmune trigger for MP development.

## Abstract

Mesenteric panniculitis (MP) is a disease of unknown etiology, causing fibrosis of the small bowel mesentery. MP is typically diagnosed incidentally with computed tomography imaging but is occasionally associated with surgery, trauma, and cancer. The prevalence of MP varies across the literature; however, it is agreed upon to be a rare diagnosis. This case describes a 34-year-old female with systemic lupus erythematosus (SLE) who presented with abdominal symptoms and was later found to have MP. We postulated that the patient’s SLE flare and adjustment in immunosuppressive medications facilitated the development of MP. This case highlights the need for further research regarding the association of MP and autoimmune conditions such as SLE.

## Linked entities

- **Diseases:** Systemic Lupus Erythematosus (MONDO:0007915), Mesenteric Panniculitis (MONDO:0016544)

## Full-text entities

- **Diseases:** fibrosis (MESH:D005355), cancer (MESH:D009369), autoimmune conditions (MESH:D001327), MP (MESH:D015436), trauma (MESH:D014947), SLE (MESH:D008180), abdominal (MESH:D000007)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11980525/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11980525/full.md

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Source: https://tomesphere.com/paper/PMC11980525