# Hand, Foot, and Mouth Disease in a Patient With Psoriasis: A Case Report

## TL;DR

A 48-year-old man with psoriasis developed hand, foot, and mouth disease caused by enterovirus A71, highlighting the need for awareness of this condition in adults with chronic skin diseases.

## Contribution

This case report presents a rare instance of HFMD in an adult with psoriasis and no known exposure, emphasizing diagnostic considerations for similar cases.

## Key findings

- The patient presented with painful vesicles and blisters consistent with HFMD.
- Blood tests confirmed enterovirus A71 infection as the cause.
- The case underscores the risk of worsening chronic skin conditions during HFMD.

## Abstract

Hand, foot, and mouth disease (HFMD) is a viral infection commonly found in children but rare in adults. Patients with chronic skin conditions may worsen after an inoculation with an infectious agent with cutaneous tropism. The present case reports a 48-year-old male patient with a history of plaque psoriasis, with no identifiable epidemiological contacts, who presented at a primary health care consultation with painful vesicles, blisters, and pustules in the perioral region, elbows, hands, and soles of the feet. He was also observed in the hospital emergency department, where blood tests confirmed an enterovirus A71 infection. The patient was subsequently followed up in a dermatology consultation. This case report emphasizes the need for health professionals to consider HFMD in adults with unexplained cutaneous lesions with oral symptoms, especially when chronic dermatological diseases are present, due to the risk of their worsening.