# Disease Prediction Using Machine Learning on Smartphone-Based Eye, Skin, and Voice Data: Scoping Review

**Authors:** Research Dawadi, Mai Inoue, Jie Ting Tay, Agustin Martin-Morales, Thien Vu, Michihiro Araki

PMC · DOI: 10.2196/59094 · 2025-03-25

## TL;DR

This review explores how smartphone data from eye, skin, and voice can be used with machine learning to predict diseases, summarizing 49 studies.

## Contribution

The paper provides a structured overview of smartphone-based disease prediction using machine learning, categorizing studies by data source and methods.

## Key findings

- 49 relevant studies were identified, using 31 databases and 24 machine learning methods.
- Studies focused on smartphone-derived data from voice, skin, and eye for disease prediction.
- Publicly available databases and experimental data collection were both common approaches.

## Abstract

The application of machine learning methods to data generated by ubiquitous devices like smartphones presents an opportunity to enhance the quality of health care and diagnostics. Smartphones are ideal for gathering data easily, providing quick feedback on diagnoses, and proposing interventions for health improvement.

We reviewed the existing literature to gather studies that have used machine learning models with smartphone-derived data for the prediction and diagnosis of health anomalies. We divided the studies into those that used machine learning models by conducting experiments to retrieve data and predict diseases, and those that used machine learning models on publicly available databases. The details of databases, experiments, and machine learning models are intended to help researchers working in the fields of machine learning and artificial intelligence in the health care domain. Researchers can use the information to design their experiments or determine the databases they could analyze.

A comprehensive search of the PubMed and IEEE Xplore databases was conducted, and an in-house keyword screening method was used to filter the articles based on the content of their titles and abstracts. Subsequently, studies related to the 3 areas of voice, skin, and eye were selected and analyzed based on how data for machine learning models were extracted (ie, the use of publicly available databases or through experiments). The machine learning methods used in each study were also noted.

A total of 49 studies were identified as being relevant to the topic of interest, and among these studies, there were 31 different databases and 24 different machine learning methods.

The results provide a better understanding of how smartphone data are collected for predicting different diseases and what kinds of machine learning methods are used on these data. Similarly, publicly available databases having smartphone-based data that can be used for the diagnosis of various diseases have been presented. Our screening method could be used or improved in future studies, and our findings could be used as a reference to conduct similar studies, experiments, or statistical analyses.

## Full-text entities

- **Diseases:** bronchitis (MESH:D001991), psychiatric (MESH:D001523), asthma (MESH:D001249), GBC (MESH:D000141), eye-, skin-, and voice-related diseases (MESH:D014832), fatigue (MESH:D005221), cataract (MESH:D002386), spontaneous abortion (MESH:D000022), TBI (MESH:D000070642), Illness (MESH:D002908), ASD (MESH:D000067877), Neonatal jaundice (MESH:D007567), gaze (MESH:D015835), skin abnormalities (MESH:D012868), Snoring (MESH:D012913), PD (MESH:D010300), wheezing (MESH:D012135), colic cries (MESH:D003085), schizophrenia (MESH:D012559), respiratory diseases (MESH:D012140), Diabetic retinopathy (MESH:D003930), skin cancer (MESH:D012878), eye diseases (MESH:D005128), blindness (MESH:D001766), heart diseases (MESH:D006331), cancer (MESH:D009369), pneumonia (MESH:D011014), melanoma (MESH:D008545), Bipolar Illness (MESH:D001714), depressed mood (MESH:D003866), autism (MESH:D001321), major depressive disorder (MESH:D003865), pain (MESH:D010146), respiratory infection (MESH:D012141), COVID-19 (MESH:D000086382), disease (MESH:D004194), lung anomaly (MESH:D008171), vision-related problems (MESH:D014786), anxiety (MESH:D001007), diabetes (MESH:D003920), Cough (MESH:D003371), breast cancer (MESH:D001943), LSTM (MESH:D000088562), retinoblastoma (MESH:D012175), jaundice (MESH:D007565), Acne (MESH:D000152), skin (MESH:D012871), digestive diseases (MESH:D004066)
- **Chemicals:** DNN (-), bilirubin (MESH:D001663)
- **Species:** Canis lupus familiaris (dog, subspecies) [taxon 9615], Homo sapiens (human, species) [taxon 9606], Felis catus (cat, species) [taxon 9685]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11979540/full.md

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Source: https://tomesphere.com/paper/PMC11979540