Complete Molar Pregnancy in a 50-Year-Old Postmenopausal Woman

TL;DR

A rare case of complete molar pregnancy is reported in a 50-year-old postmenopausal woman, highlighting the importance of accurate diagnosis in older patients.

Contribution

This case report adds to the limited literature on gestational trophoblastic disease in postmenopausal women.

Findings

Abnormal vaginal bleeding in a postmenopausal woman was found to be due to a complete molar pregnancy.

Diagnostic imaging and elevated B-HCG levels supported the diagnosis before surgical confirmation.

Abstract

Gestational trophoblastic diseases (GTDs) are usually seen in women of reproductive age, but rarely, they can also be observed in postmenopausal women. In a postmenopausal woman presenting with abnormal vaginal bleeding, the differential diagnosis of gestational trophoblastic disease using histopathological, clinical, and radiological methods is important to prevent delays in treatment.

A 50-year-old female patient presented to our clinic with complaints of abnormal vaginal bleeding. Ultrasound imaging revealed a mass lesion in the endometrial cavity consistent with a molar pregnancy. Furthermore, the biochemical value of beta-human chorionic gonadotropin (B-HCG) was 353,761 IU/L, supporting the diagnosis. For further evaluation, the patient underwent computed tomography and magnetic resonance imaging. Additional imaging supported the diagnosis. Based on these results, the patient underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy. Pathology results confirmed a complete molar pregnancy.

In this case report, we present the clinical and radiological approach in the differential diagnosis of gestational trophoblastic disease in a 50-year-old female patient.

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