# Sequential MRI as a Diagnostic Tool for Follow‐Up of Hyaluronic Acid Dermal Filler, in a Woman Who Underwent Radiation Therapy for Oral Cancer

**Authors:** Gloria Bettini, Ferdinando De Negri, Roberto Amore, Sergio Rexhep Tari, Antonio Scarano

PMC · DOI: 10.1002/ccr3.70402 · 2025-04-08

## TL;DR

This paper explores how MRI can help track hyaluronic acid fillers in a cancer patient, avoiding confusion with other medical issues.

## Contribution

The study highlights the MRI characteristics of hyaluronic acid fillers to aid accurate diagnosis in post-radiation therapy patients.

## Key findings

- Hyaluronic acid appears strongly hyperintense on MRI due to its water-like signal.
- The study emphasizes the importance of recognizing filler signals to avoid misdiagnosis in cancer patients.

## Abstract

The present investigation aimed to inform the radiologists about the imaging features of injectable fillers in order not to confound these with true pathology or vice versa in order not to miss true pathology obscured by filler injections. The signal of hyaluronic acid closely follows the water signal because of its composition and its hydrophilic nature and appears strongly hyperintense.

## Linked entities

- **Diseases:** oral cancer (MONDO:0023644)

## Full-text entities

- **Diseases:** Oral Cancer (MESH:D009062)
- **Chemicals:** Hyaluronic Acid (MESH:D006820), Filler (-), water (MESH:D014867)

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11978728/full.md

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Source: https://tomesphere.com/paper/PMC11978728