# Advances in the study of the correlation between balanoposthitis and skin microecology

**Authors:** Mingyue Wang, Xinghua Gao, Li Zhang

PMC · DOI: 10.3389/fmicb.2025.1564675 · 2025-03-26

## TL;DR

This paper explores how skin microecology influences balanoposthitis, a common genital skin condition, and highlights recent advances in understanding its causes.

## Contribution

The paper provides a summary of recent research progress linking balanoposthitis to microbial imbalances and suggests future directions for immunological studies.

## Key findings

- High-throughput sequencing has improved understanding of prepuce and glans penis microbial colonization.
- Floral imbalance is linked to the development of balanoposthitis.
- The paper outlines directions for future research on immunological mechanisms.

## Abstract

Balanoposthitis is a common heterogeneous skin condition involving the glans penis and prepuce, and is seen from infancy to old age. Its predisposing factors are intertrigo, lengthy foreskin, localized irritation, and mucosal injury. The itching and skin inflammation at the glans penis seriously affects the quality of life of patients. As a result of advances in high-throughput sequencing technology, the prepuce microbial colonization patterns and glans penis are now known better. Previous studies have shown that an imbalance of flora can cause balanoposthitis. This article summarizes the progress of research on balanoposthitis and skin microecology, and provides a direction for the subsequent exploration of immunological mechanisms in balanoposthitis.

## Linked entities

- **Diseases:** balanoposthitis (MONDO:0001618)

## Full-text entities

- **Diseases:** itching (MESH:D011537), mucosal injury (MESH:D052016), skin condition (MESH:D012871), skin inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC11978672/full.md

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Source: https://tomesphere.com/paper/PMC11978672