Exploring Central Venous Thrombosis as a Rare Postinfectious Complication of Dengue: A Case Report

TL;DR

This case report describes a rare instance of central venous thrombosis following dengue fever, highlighting the need for awareness of thrombotic complications in dengue patients.

Contribution

The paper presents a novel case of central venous thrombosis as a postinfectious complication of dengue fever.

Findings

A 38-year-old male with dengue fever developed central venous thrombosis involving the superior straight sinus.

Anticoagulant therapy led to improvement in neurological symptoms and partial recanalization of the thrombosed sinus.

Abstract

Dengue fever, caused by a flavivirus transmitted through Aedes mosquitoes, presents a spectrum of clinical manifestations ranging from mild to severe. Several neurological complications, including encephalopathy and encephalitis, have been increasingly recognized. Here, we report a case of central venous thrombosis (CVT) as a postinfectious complication of dengue fever. A 38-year-old previously healthy male presented with classic dengue symptoms and later developed persistent headaches and visual disturbances. Neurological examination revealed papilledema, and imaging confirmed CVT involving the superior straight sinus. Prompt initiation of anticoagulant therapy led to gradual improvement in neurological symptoms and partial recanalization of the thrombosed sinus. Our case underscores the importance of considering thrombotic complications in dengue infections, despite the predominance of hemorrhagic manifestations. Understanding pathophysiology and appropriate management of thrombotic events in dengue fever is crucial for favorable patient outcomes.

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