# Development of a job satisfaction measure for clinical research professionals: A mixed methods approach

**Authors:** Jacqueline M. Knapke, John Kues, Spencer K. Harris, Denise C. Snyder, Stephanie A. Freel, Harini Pallerla, Jessica Fritter, Angela Mendell, Carolynn T. Jones

PMC · DOI: 10.1017/cts.2025.34 · Journal of Clinical and Translational Science · 2025-03-24

## TL;DR

This study creates a job satisfaction survey for clinical research professionals to help improve retention in academic medical centers.

## Contribution

The study introduces a validated job satisfaction measure for clinical research professionals using mixed methods.

## Key findings

- Seven key factors influencing job satisfaction were identified through principal components analysis.
- Self-efficacy and pride in work were top quantitative factors, while work complexity and salary were top qualitative factors.
- Professional development opportunities emerged as important themes in qualitative responses.

## Abstract

Clinical research professionals (CRPs) are essential members of research teams serving in multiple job roles. However, recent turnover rates have reached crisis proportions, negatively impacting clinical trial metrics. Gaining an understanding of job satisfaction factors among CRPs working at academic medical centers (AMCs) can provide insights into retention efforts.

A survey instrument was developed to measure key factors related to CRP job satisfaction and retention. The survey included 47 rating items in addition to demographic questions. An open-text question solicited respondents to provide their top three factors for job satisfaction. The survey was distributed through listservs of three large AMCs. Here, we present a factor analysis of the instrument and quantitative and qualitative results of the subsequent survey.

A total of 484 CRPs responded to the survey. A principal components analysis with Varimax rotation was performed on the 47 rating items. The analysis resulted in seven key factors and the survey instrument was reduced to 25 rating items. Self-efficacy and pride in work were top ranked in the quantitative results; work complexity and stress and salary and benefits were top ranked in the qualitative findings. Opportunities for education and professional development were also themes in the qualitative data.

This study addresses the need for a tool to measure job satisfaction of CRPs. This tool may be useful for additional validation studies and research to measure the effectiveness of improvement initiatives to address CRP job satisfaction and retention.

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}

## Full text

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## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11975783/full.md

## References

37 references — full list in the complete paper: https://tomesphere.com/paper/PMC11975783/full.md

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Source: https://tomesphere.com/paper/PMC11975783