# Blasto in the Bronx: An Unusual Case of Severe Cutaneous Blastomycosis in New York City

**Authors:** Sabirah N Kasule, Andrea K Thet, Srikaran Bojja, Abolfazl Sodagar, Joshua Davidson, Donald D Rudikoff, Lendelle Raymond, Cosmina B Zeana

PMC · DOI: 10.7759/cureus.80251 · Cureus · 2025-03-08

## TL;DR

A New York City resident developed severe skin blastomycosis without recent travel to endemic areas, marking the first reported local case.

## Contribution

This is the first documented case of blastomycosis acquired endemically in New York City.

## Key findings

- A patient presented with severe cutaneous blastomycosis confirmed via culture and pathology.
- The patient had no travel history outside NYC, suggesting local acquisition of the infection.
- The infection was successfully treated with oral itraconazole.

## Abstract

Urban cases of blastomycosis are extremely rare and usually involve an individual or individuals with recent travel to, and outdoor exposure in, an endemic area. We report a case of severe cutaneous blastomycosis in a New York City resident. He presented to our hospital in 2023 with multiple cavitary lung nodules and a large area of fungating lesions on his back that had been progressing for a month. Cultures and pathology from the skin lesions confirmed a diagnosis of cutaneous blastomycosis, and the patient was successfully treated with a prolonged course of oral itraconazole. Given no travel history outside of the five boroughs, we believe the patient acquired the infection endemically and is the first published case of blastomycosis acquired in New York City.

## Linked entities

- **Chemicals:** itraconazole (PubChem CID 55283)
- **Diseases:** blastomycosis (MONDO:0005672)

## Full-text entities

- **Diseases:** Cutaneous Blastomycosis (MESH:D001759), skin (MESH:D012871), infection (MESH:D007239)
- **Chemicals:** itraconazole (MESH:D017964)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11975145/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11975145/full.md

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Source: https://tomesphere.com/paper/PMC11975145