# Treatment of Haemophilus influenzae Serotype A (Hia) Meningitis in a Pediatric Patient: A Case Report

**Authors:** Matthew Thomas, Shivang Patel, Harthik Kambhampati, Miriam Thomas

PMC · DOI: 10.7759/cureus.80253 · Cureus · 2025-03-08

## TL;DR

A 10-week-old infant with severe Hia meningitis and complications made a full recovery after timely treatment and multidisciplinary care.

## Contribution

This case report adds to the limited literature on Hia meningitis in infants and emphasizes the importance of timely diagnosis and management.

## Key findings

- The patient presented with Hia meningitis, cerebritis, seizures, and CADVT.
- Empiric treatment was followed by tailored therapy based on culture results.
- The patient showed complete recovery with no long-term complications after two years.

## Abstract

Haemophilus influenzae serotype A (Hia) meningitis is a rare but severe pediatric infection, with significant risks of mortality and long-term complications. Here, we describe a 10-week-old male presenting with Hia meningitis complicated by cerebritis, seizures, and central venous catheter-related deep vein thrombosis (CADVT). The patient initially presented with fever, irritability, and feeding difficulties and was later found to have significant laboratory abnormalities and cerebrospinal fluid (CSF) findings suggestive of bacterial meningitis. This case highlights the empiric treatment of pediatric meningitis, tailored and adjunctive treatments based on culture results, and other thrombotic and neurological complications. Despite high morbidity risks, the patient demonstrated complete clinical recovery at two years and showed no signs of long-term sequelae. This case emphasizes the evolving epidemiology of Hia and the importance of timely diagnosis and multidisciplinary management in severe pediatric infections, to ensure the minimization of negative externalities.

## Linked entities

- **Diseases:** cerebritis (MONDO:0002645), bacterial meningitis (MONDO:0006670)

## Full-text entities

- **Diseases:** cerebritis (MESH:D002547), Haemophilus influenzae Serotype A (Hia (MESH:D006192), irritability (MESH:D001523), CADVT (MESH:D020246), bacterial meningitis (MESH:D016920), seizures (MESH:D012640), infection (MESH:D007239), thrombotic and neurological complications (MESH:D002493), Meningitis (MESH:D008580), fever (MESH:D005334), Hia meningitis (MESH:D008583)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11975126/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC11975126/full.md

---
Source: https://tomesphere.com/paper/PMC11975126