# Pseudotumor Phenotype of Sarcoidosis

**Authors:** Mohamed Lakhal, Meriem Rhazari, Sara Gartini, Mohammed Meziane, Afaf Thouil, Amal Bennani, Hatim Kouismi

PMC · DOI: 10.7759/cureus.80245 · Cureus · 2025-03-08

## TL;DR

This paper presents a case of sarcoidosis that appeared like a tumor on imaging, emphasizing the importance of histological confirmation for accurate diagnosis.

## Contribution

The paper highlights the pseudo-tumoral presentation of sarcoidosis as a diagnostic challenge and underscores the need for histopathological examination.

## Key findings

- Sarcoidosis can present with a pseudo-tumoral appearance on imaging.
- Histopathological confirmation is essential to differentiate sarcoidosis from tumors.
- A subtle clinical presentation may contrast with significant radiological findings in sarcoidosis.

## Abstract

Sarcoidosis is a benign multi-system granulomatous disease of unknown etiology. It can occasionally present with a pseudo-tumoral appearance, constituting a diagnostic pitfall that should be considered. We report the case of an 84-year-old patient with no significant medical history, admitted for the management of chronic dyspnea associated with chest pain evolving over the past six months, in the context of a preserved general condition. A chest CT scan revealed a pulmonary process, and the histopathological examination confirmed sarcoidosis. Through this case, we highlight the unique presentation of pulmonary sarcoidosis with a pseudo-tumoral pattern, which is often challenging to diagnose. The discrepancy between the subtle clinical presentation and the extent of radiological lesions should, however, raise suspicion of this diagnosis. Histological confirmation is necessary to rule out other potential etiologies, particularly tumors.

## Linked entities

- **Diseases:** sarcoidosis (MONDO:0008399)

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11974230/full.md

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Source: https://tomesphere.com/paper/PMC11974230