# PET/MRI is superior to PET/CT in detecting oesophago and gastric carcinomas: a meta-analysis

**Authors:** Bo Peng, Hui Sun, Jian Hou, Jian-Xing Luo

PMC · DOI: 10.1186/s40644-025-00871-3 · Cancer Imaging · 2025-04-07

## TL;DR

PET/MRI is better than PET/CT for detecting oesophago and gastric cancers, with similar staging accuracy and less radiation.

## Contribution

Demonstrates PET/MRI's superior detection accuracy for these cancers compared to PET/CT.

## Key findings

- PET/MRI showed higher sensitivity in primary lesion detection (RR = 1.14, 95% CI 1.01–1.29).
- PET/MRI and PET/CT had no significant differences in TNM staging accuracy.
- PET/MRI reduces radiation exposure compared to PET/CT.

## Abstract

To compare the accuracy rates of the detection and staging of oesophago and gastric carcinomas between PET/MRI and PET/CT.

An extensive librarian-led literature search of PubMed, Embase, Web of Science, the Cochrane Central Library, and CNKI was performed and a meta-analysis was done.

Six studies, including 123 participants, were analyzed. PET/MRI had a comparatively high sensitivity in primary lesion detection compared with PET/CT. (RR = 1.14, 95% CI 1.01–1.29, P = 0.036).PET/MRI had no significant statistical differences in all aspects of TNM staging compared with PET/CT.

This systematic review confirmed the advantage of PET/MRI in detecting oesophago and gastric carcinomas.Compared with PET/CT, it can reduce unnecessary radiation exposure and can be used in relevant patients without contraindications of MRI.

## Full-text entities

- **Diseases:** oesophago and gastric carcinomas (MESH:D013274)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11974111/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC11974111/full.md

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Source: https://tomesphere.com/paper/PMC11974111