# Overcoming challenges in ovarian visualization: a case report of a magnetic resonance imaging–guided oocyte retrieval resulting in live birth

**Authors:** Michael F. Neblett, Hakan Kula, David L. Walker, Katherine J. Nunemacher, David A. Woodrum, Samir N. Babayev

PMC · DOI: 10.1016/j.xfre.2025.01.007 · F&S Reports · 2025-01-21

## TL;DR

MRI-guided oocyte retrieval successfully enabled a live birth in a patient with complex pelvic anatomy and limited ovarian visibility.

## Contribution

Demonstrates the feasibility of MRI-guided oocyte retrieval in cases where traditional ultrasound methods are ineffective.

## Key findings

- MRI-guided retrieval successfully obtained two oocytes from five follicles.
- A single blastocyst developed and resulted in a live birth via embryo transfer.
- MRI guidance may be a viable alternative for patients with complex pelvic anatomy.

## Abstract

To report a successful case of magnetic resonance imaging (MRI)–guided oocyte retrieval in a patient with challenging pelvic anatomy, extensive adhesive disease, and diminished ovarian reserve, necessitated by the inability to visualize the ovaries using transvaginal or transabdominal ultrasound.

Case report.

A 33-year-old nulligravid woman with a history of ulcerative colitis, multiple pelvic and abdominal surgeries, and significant pelvic adhesive disease.

Controlled ovarian stimulation was initiated using a gonadotropin-releasing hormone antagonist protocol, followed by sequential MRI and MRI-guided oocyte retrieval due to challenges in visualizing and accessing the ovaries.

Successful oocyte retrieval under MRI guidance.

Two oocytes were retrieved from 5 aspirated follicles using MRI guidance. Both underwent intracytoplasmic sperm injection, resulting in the development of a single blastocyst, which led to a live birth via embryo transfer to a gestational carrier.

Magnetic resonance imaging–guided oocyte retrieval represents a potential technique for patients with complex pelvic anatomy or extensive adhesive disease, where traditional ultrasound-guided approaches may be inadequate. Interdisciplinary collaboration and individualized care are crucial in optimizing outcomes for patients undergoing assisted reproduction, particularly those with challenging medical histories. Further studies comparing MRI-guided and traditional ultrasound-guided oocyte retrieval in challenging cases are warranted to determine the optimal approach for these patients.

## Linked entities

- **Diseases:** ulcerative colitis (MONDO:0005101)

## Full-text entities

- **Diseases:** ulcerative colitis (MESH:D003093), pelvic adhesive disease (MESH:D000292), adhesive disease (MESH:D000267)
- **Chemicals:** gonadotropin-releasing hormone antagonist (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC11973817/full.md

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Source: https://tomesphere.com/paper/PMC11973817