# Role of mechanical hysteroscopic tissue removal system in post-molar gestational trophoblastic neoplasia management: case report and literature review

**Authors:** Sophie Schoenen, Katty Delbecque, Frédéric Kridelka, Florence Hanocq, Frédéric Goffin, Patricia Nervo

PMC · DOI: 10.1093/jscr/rjaf190 · Journal of Surgical Case Reports · 2025-04-06

## TL;DR

This case report explores using a mechanical hysteroscopic system to treat post-molar neoplasia, a rare condition after molar pregnancy, as an alternative to traditional methods.

## Contribution

The paper presents a novel use of a mechanical hysteroscopic tissue removal system for managing low-risk post-molar neoplasia.

## Key findings

- A patient with low-risk post-molar neoplasia was successfully treated with hysteroscopic resection.
- Hysteroscopic resection may serve as an alternative to second curettage in selected cases.
- The literature on this approach remains limited, requiring further study.

## Abstract

Complete hydatidiform moles are precancerous gestational trophoblastic diseases, with 15%–20% progressing to post-molar neoplasia. The gold standard treatment of low-risk neoplasia is single-agent chemotherapy. A second curettage is an alternative to avoid chemotherapy; hysteroscopic resection is not described in the guidelines. We report a case of post-molar neoplasia treated using a mechanical hysteroscopic tissue removal system (TruClear°) and review the limited literature on the subject. A patient was diagnosed with low-risk post-molar neoplasia in our department. Ultrasound evaluation revealed uterine trophoblastic retention, which was managed with mechanical hysteroscopic resection. In conclusion, hysteroscopic resection could be a potential alternative to second curettage in highly selected cases of low-risk post-molar neoplasia.

## Linked entities

- **Diseases:** complete hydatidiform mole (MONDO:0016785)

## Full-text entities

- **Diseases:** precancerous (MESH:D011230), gestational trophoblastic diseases (MESH:D031901), hydatidiform moles (MESH:D006828), neoplasia (MESH:D009369), trophoblastic retention (MESH:D014328), post (MESH:D000094025)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11972626/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC11972626/full.md

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Source: https://tomesphere.com/paper/PMC11972626