# Rare Association of Disseminated Cutaneous Leishmaniasis With Urethral Stricture: A Case Report

**Authors:** Siddharta Saxena, Vikas Kumar Panwar, Ankur Mittal, Mohammed Taher Mujahid, Mehul Agarwal, Nalin K Srivastava, Avin Singhal

PMC · DOI: 10.7759/cureus.80179 · Cureus · 2025-03-06

## TL;DR

A rare case of leishmaniasis caused urogenital complications, successfully treated with drugs and surgery.

## Contribution

Reports a rare case linking disseminated cutaneous leishmaniasis with urethral stricture and fistula.

## Key findings

- Leishmaniasis can cause urogenital complications like urethral stricture and fistula.
- Combined medical and surgical treatment successfully managed the condition.
- Histopathology confirmed Leishmania parasites in the patient.

## Abstract

Leishmaniasis, a parasitic disease transmitted by sandflies, rarely presents with urogenital complications. This case highlights an unusual presentation of disseminated cutaneous leishmaniasis with urethral involvement. A 42-year-old male from an endemic region presented with macular-papules-nodular lesions on lips, nose, and tongue, accompanied by genital ulcers and urinary complications. Histopathological examination confirmed Leishmania parasites. The patient developed urethral stricture and urethrocutaneous fistula, which were managed successfully with systemic amphotericin B and staged urethroplasty. This case emphasizes the importance of considering leishmaniasis in the differential diagnosis of urogenital manifestations in endemic regions. The successful outcome demonstrates the effectiveness of combined medical and surgical management.

## Linked entities

- **Chemicals:** amphotericin B (PubChem CID 1972)
- **Diseases:** leishmaniasis (MONDO:0011989), urethral stricture (MONDO:0002127)

## Full-text entities

- **Diseases:** complications (MESH:D008107), Cutaneous Leishmaniasis (MESH:D016773), fistula (MESH:D005402), Urethral Stricture (MESH:D014525), Leishmaniasis (MESH:D007896), genital ulcers (MESH:D014456)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11972424/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC11972424/full.md

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Source: https://tomesphere.com/paper/PMC11972424