# Group A Streptococcus Bacteraemia Presenting as Acute Limb Ischaemia in a Neonate: A Case Report

**Authors:** Muhammad Moiz Muzaffar, Syahin Samani, Peter Van Der Velde

PMC · DOI: 10.7759/cureus.80170 · Cureus · 2025-03-06

## TL;DR

A neonate with Group A Streptococcus bacteraemia presented with limb discoloration and was successfully treated with antibiotics and anticoagulation.

## Contribution

This case report highlights a rare presentation of neonatal sepsis caused by GAS and emphasizes the importance of early treatment.

## Key findings

- A three-week-old neonate showed improvement after treatment for GAS septicaemia and septic emboli.
- Mild residual hyperpigmentation and minor tissue loss were observed at the two-month follow-up.
- Early recognition of rare GAS presentations can prevent severe complications in neonates.

## Abstract

The reported incidence of Group A Streptococcus (GAS) bacteraemia is generally low, though it remains a significant concern. We report the case of a three-week-old neonate who presented with blackish discolouration of her toes and a rash, later diagnosed with invasive GAS septicaemia and septic emboli. She received antibiotics and anticoagulation, showing significant improvement, with mild residual hyperpigmentation and minor tissue loss at the two-month follow-up. Our case report highlights that early recognition and treatment of neonatal sepsis, including rare presentations such as septic emboli from pathogens like GAS, are critical for preventing severe complications and ensuring favourable long-term outcomes.

## Full-text entities

- **Diseases:** septic emboli (MESH:D020766), sepsis (MESH:D018805), bacteraemia (MESH:C531821), Group A Streptococcus Bacteraemia (MESH:D011008), hyperpigmentation (MESH:D017495), Limb Ischaemia (MESH:D001259), rash (MESH:D005076)

## Full text

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## Figures

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## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11972120/full.md

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Source: https://tomesphere.com/paper/PMC11972120