# First person – Casey Griffin

## TL;DR

Casey Griffin discusses her research on how deleting the sf3b4 gene affects facial development and survival in a paper published in Disease Models & Mechanisms.

## Contribution

The study reveals that deletion of sf3b4 leads to splicing defects and gene dysregulation impacting craniofacial development.

## Key findings

- Deleting sf3b4 causes splicing defects and gene dysregulation.
- These defects disrupt craniofacial development and affect survival.
- The research highlights the role of sf3b4 in developmental biology.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Casey Griffin is first author on ‘
Deletion of sf3b4 causes splicing defects and gene dysregulation that disrupt craniofacial development and survival’, published in DMM. Casey is an Associate Research Scientist in the lab of Jean-Pierre Saint-Jeannet at the College of Dentistry, investigating the role of neural crest cells during the development of the face.