# First person – Caroline Beltran

## TL;DR

Caroline Beltran discusses her research on using 3D imaging to study TB lesions in mice and its implications for understanding treatment responses.

## Contribution

A novel correlative 3D imaging method for analyzing TB lesion architecture in infected mice.

## Key findings

- The method enables detailed analysis of host-pathogen interactions in TB.
- It helps unravel treatment responses in tuberculosis models.
- The approach was developed during Beltran's postdoctoral work at Stellenbosch University.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Caroline Beltran is first author on ‘
Correlative 3D imaging method for analysing lesion architecture in susceptible mice infected with Mycobacterium tuberculosis’, published in DMM. Caroline conducted the research described in this article while a postdoctoral researcher in Professor Gerhard Walzl's lab at Stellenbosch University, Cape Town, South Africa, and is now a Scientific Director at Synexa Life Sciences, Cape Town, South Africa, leveraging 3D imaging to decipher host–pathogen interactions and unravel treatment responses in tuberculosis (TB).