# First person – James D. Hurcomb and Amrita Mukherjee

## TL;DR

This paper features an interview with James D. Hurcomb and Amrita Mukherjee, who studied the intestinal toxicity of aripiprazole in fruit flies.

## Contribution

The paper presents a first-person interview highlighting their research on mitochondrial toxicity and inter-organ communication in Drosophila.

## Key findings

- Oral administration of aripiprazole to Drosophila causes intestinal toxicity.
- James and Amrita investigate inter-organ communication and metabolic responses to mitochondrial toxicity.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. James D. Hurcomb and Amrita Mukherjee are co-first authors on ‘
Oral administration of aripiprazole to Drosophila causes intestinal toxicity’, published in DMM. James is a PhD student in the lab of L. Miguel Martins at ​the MRC Toxicology Unit, University of Cambridge, Cambridge, UK, investigating inter-organ communication and whole-body metabolic response in response to mitochondrial toxicity. Amrita is a research fellow in the same lab and is interested in mitochondrial toxicity and the effect it has in different tissues and on cellular metabolism.