# Successful thrombectomy for inferior vena cava thrombosis associated with an ovarian tumor: a case report

**Authors:** Kazuki Mori, Takashi Shuto, Kenshi Yoshimura, Shinji Miyamoto, Yusuke Sato, Mamiko Okamoto, Kentaro Kai, Eiji Kobayashi

PMC · DOI: 10.1093/jscr/rjaf196 · Journal of Surgical Case Reports · 2025-04-05

## TL;DR

A 51-year-old woman with ovarian cancer and a large blood clot in her inferior vena cava underwent successful surgery to remove the tumor and clot.

## Contribution

Demonstrates the effectiveness of open thrombectomy in treating IVC thrombosis associated with ovarian tumors.

## Key findings

- Combined adnexal resection and thrombectomy enabled safe IVC filter placement.
- Postoperative anticoagulation improved deep vein thrombus and pulmonary embolism.
- Open thrombectomy remains a valid treatment despite advances in endovascular therapy.

## Abstract

A 51-year-old female patient presented with abdominal distension. Computed tomography revealed a right ovarian tumor suspicious for clinical stage IC ovarian cancer, along with a considerable inferior vena cava (IVC) thrombus extending to the Th2 level, accompanied by a deep vein thrombus and a peripheral left pulmonary embolism (PE). Preoperative IVC filter placement was deemed unfavorable due to the short distance between the renal vein and the thrombus. On the second day of hospitalization, ovarian tumor extraction, thrombectomy, and IVC filter placement were performed. Pathology of the excised tumor revealed endometrioid carcinoma. Postoperatively, anticoagulation therapy with edoxaban 30 mg/day resulted in improvement of the deep vein thrombus and PE. The concomitant adnexal resection and thrombectomy rendered the safe placement of an IVC filter feasible despite the preoperative placement being unfeasible. Open thrombectomy remains a valid treatment strategy despite advances in endovascular therapy.

## Linked entities

- **Chemicals:** edoxaban (PubChem CID 10280735)
- **Diseases:** ovarian cancer (MONDO:0005140), endometrioid carcinoma (MONDO:0005026), pulmonary embolism (MONDO:0005279)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), deep vein thrombus (MESH:D013927), ovarian cancer (MESH:D010051), abdominal distension (MESH:D000007), endometrioid carcinoma (MESH:D018269), PE (MESH:D011655), inferior vena cava (IVC) thrombus (MESH:C563013)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11971566/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC11971566/full.md

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Source: https://tomesphere.com/paper/PMC11971566