# Pseudo‐orthostatic tremor in a cat

**Authors:** Marende M. de Gier, Dian Schuil, Laurent Garosi, Mark Lowrie, Koen M. Santifort

PMC · DOI: 10.1111/jvim.17290 · Journal of Veterinary Internal Medicine · 2025-04-05

## TL;DR

A young cat showed a tremor in its hind legs when standing or moving, diagnosed as pseudo-orthostatic tremor, but treatment with medications did not improve the condition.

## Contribution

This case report describes pseudo-orthostatic tremor in a cat, a rare condition previously undocumented in felines.

## Key findings

- The cat exhibited a 6 Hz tremor in pelvic limbs when standing or extending the stifle.
- Needle electromyography confirmed the tremor characteristics in a conscious cat.
- Treatment with gabapentin and clonazepam failed to improve the condition.

## Abstract

An 11‐month‐old male castrated shorthaired cat was presented with a tremor in both pelvic limbs, which only occurred when standing (ie, countering gravity) or during active extension of the stifle. General clinical and neurological examinations were normal aside from the tremor of the pelvic limbs, which disappeared on performing a weight‐bearing lifting test. Needle electromyography of both pelvic limbs in the conscious state confirmed a low‐frequency (6 Hz) tremor. The cat was diagnosed with pseudo‐orthostatic tremor. The tremor amplitude waxed and waned over time. The cat remained ambulatory and playful, but often assumed lateral recumbency and seemed to have difficulty jumping. Treatment with gabapentin (10‐20 mg/kg PO q8h) for 3 weeks followed by clonazepam (0.1 mg/kg PO q12h) for 1 day (with unacceptable adverse effects) did not result in improvement.

## Linked entities

- **Chemicals:** gabapentin (PubChem CID 3446), clonazepam (PubChem CID 2802)

## Full-text entities

- **Diseases:** tremor (MESH:D014202), Pseudo-orthostatic tremor (MESH:C536418)
- **Chemicals:** gabapentin (MESH:D000077206), clonazepam (MESH:D002998)
- **Species:** Felis catus (cat, species) [taxon 9685]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11971530/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC11971530/full.md

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Source: https://tomesphere.com/paper/PMC11971530