# Health-Related Quality of Life Among Type 2 Diabetes Patients With Depressive Symptoms in Vietnam

**Authors:** Nguyen Tran Kien, Nguyen Phuong Hoa, Ha Huu Tung, Kris Van den Broeck, Johan Wens

PMC · DOI: 10.1155/jdr/6992121 · Journal of Diabetes Research · 2025-03-28

## TL;DR

This study explores how depression affects the quality of life for people with Type 2 diabetes in Vietnam.

## Contribution

It highlights the significant impact of depressive symptoms on health-related quality of life in a resource-limited setting.

## Key findings

- 45.2% of Type 2 diabetes patients showed depressive symptoms ranging from mild to severe.
- Depressive symptoms were strongly linked to lower physical and overall quality of life scores.
- PHQ-9 scores were identified as a strong predictor of reduced health-related quality of life.

## Abstract

Background: This study investigates the impact of Type 2 diabetes mellitus (T2DM) and depressive symptoms on the health-related quality of life (HRQoL) among patients at the Agricultural General Hospital in Hanoi, Vietnam. The research explores the interconnections between chronic physical conditions and mental health within a resource-constrained healthcare environment.

Methods: A cross-sectional survey was conducted with 516 T2DM patients using the SF-36 to assess HRQoL and the PHQ-9 to measure depressive symptoms. The study examined the prevalence of depressive symptoms and their correlation with various HRQoL components.

Results: Among the participants, 45.2% exhibited depressive symptoms from mild to severe levels. Significant disparities in HRQoL scores were observed, particularly in physical composite and overall quality of life scores between T2DM with and without depressive symptoms. Statistical analysis highlighted that depressive symptoms significantly diminish HRQoL, with the PHQ-9 scores serving as a robust predictor.

Conclusion: The findings underscore the critical need for integrated care approaches that include mental health support for T2DM patients. Routine screening for depressive symptoms should be a component of diabetes management protocols to improve overall patient outcomes. Further longitudinal research is needed to confirm these findings and develop effective interventions.

## Linked entities

- **Diseases:** Type 2 diabetes mellitus (MONDO:0005148)

## Full-text entities

- **Diseases:** T2DM (MESH:D003924), Depressive Symptoms (MESH:D003866), diabetes (MESH:D003920)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC11971502/full.md

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Source: https://tomesphere.com/paper/PMC11971502