# De Novo Genome Assembly and Comparative Genome Analysis of the Novel Human Fungal Pathogen Trichosporon austroamericanum Type-Strain CBS 17435

**Authors:** Elaine C. Francisco, Marie Desnos-Ollivier, Bert Gerrits van den Ende, Ferry Hagen

PMC · DOI: 10.1007/s11046-025-00942-w · Mycopathologia · 2025-04-04

## TL;DR

This paper presents the genome assembly of a new human fungal pathogen, Trichosporon austroamericanum, and compares it to a related species.

## Contribution

The study provides the first de novo genome assembly of Trichosporon austroamericanum type-strain CBS 17435 using nanopore long-read technology.

## Key findings

- The genome of Trichosporon austroamericanum was assembled using nanopore sequencing.
- Comparative analysis revealed genetic differences between T. austroamericanum and T. inkin.

## Abstract

Trichosporon austroamericanum is a recently described species recognized for its emerging clinical significance in invasive trichosporonosis. In this study, we present the nanopore long-read-based de novo genome assembly of the type-strain CBS 17435. Additionally, we performed genomic comparative analyses with its closest relative, Trichosporon inkin.

## Linked entities

- **Species:** Trichosporon austroamericanum (taxon 3080368), Trichosporon inkin (taxon 82517)

## Full-text entities

- **Diseases:** trichosporonosis (MESH:D060586)
- **Species:** Trichosporon inkin (species) [taxon 82517], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC11971232/full.md

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Source: https://tomesphere.com/paper/PMC11971232