# Metastatic Breast Cancer to the Esophagus Causing Pseudoachalasia

**Authors:** Garrett Teskey, Alexander Prevallet, Rohit Khanna, Franklin Chung-Han Tsai, Walter James Coyle

PMC · DOI: 10.14309/crj.0000000000001666 · ACG Case Reports Journal · 2025-04-04

## TL;DR

A 65-year-old woman with metastatic breast cancer showed symptoms resembling achalasia, but a biopsy revealed cancer had spread to her esophagus.

## Contribution

This case highlights metastatic breast cancer to the esophagus presenting as pseudoachalasia, a rare and diagnostic challenge.

## Key findings

- The patient's symptoms and imaging suggested achalasia, but a biopsy confirmed metastatic breast cancer.
- Endosonography-guided biopsy was crucial for accurate diagnosis in this atypical case.

## Abstract

A unique case involving a 65-year-old woman with recurrent hormone-positive, HER-2-negative breast cancer stage IV (T2N2M1) with known metastases to the bone presented with worsening dysphagia and esophageal wall thickening on imaging masquerading as achalasia. However, endosonography (EUS)-guided biopsy of the esophagus wall demonstrated metastatic breast cancer to the esophagus causing pseudoachalasia.

## Linked entities

- **Diseases:** breast cancer (MONDO:0004989), achalasia (MONDO:0008698)

## Full-text entities

- **Genes:** ERBB2 (erb-b2 receptor tyrosine kinase 2) [NCBI Gene 2064] {aka CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19}
- **Diseases:** achalasia (MESH:D004931), Breast Cancer (MESH:D001943), dysphagia (MESH:D003680), metastases (MESH:D009362)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11970811/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11970811/full.md

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Source: https://tomesphere.com/paper/PMC11970811