# Short-term outcome following postoperative enhanced recovery implementation in patients with perforated peptic ulcer

**Authors:** Amna A. Desoky, Mahmoud T. Ayoub, Neama M. Mostafa, Eman M. Hashem, Mona A. Mohammed

PMC · DOI: 10.1186/s40001-025-02432-7 · European Journal of Medical Research · 2025-04-04

## TL;DR

This study shows that using enhanced recovery after surgery improves recovery and quality of life in patients with perforated peptic ulcers.

## Contribution

The study demonstrates the effectiveness of enhanced recovery protocols in reducing complications and improving outcomes for perforated peptic ulcer patients.

## Key findings

- Patients with enhanced recovery had earlier bowel movements and shorter hospital stays.
- The study group had significantly fewer postoperative complications and better quality of life scores.
- Gastrointestinal functional recovery improved with enhanced recovery protocols.

## Abstract

To evaluate the short-term outcome following postoperative enhanced recovery implementation in patients with perforated peptic ulcer.

Quasi-experimental research design was utilized. Thirty patients received postoperative enhanced recovery after open surgical repair of perforated peptic ulcer compared with control group who received routine care. Patient assessment sheet and gastrointestinal quality of life index were the tools used for data collection.

The mean age was 40.43 ± 8.39 years for the study group and 39.53 ± 8.08 for the control group (56.7%, 70%), respectively, were males. The study group demonstrated early first bowel movement, flatus and stool passage (8.1 ± 1.16 (h), 12.6 ± 2.46 (h), and 2.47 ± 0.82 (days)), respectively, compared to control group (10 ± 1.11, 15.1 ± 2.04, and 3.57 ± 0.82). A significant reduction (6.93 ± 1.29 vs. 12.3 ± 4.96 (days)) and (30% vs. 60%) in hospital length of stay and postoperative complications among study group compared to control group (P < 0.01). The mean scores (56.17 ± 13.78 and 72.6 ± 11.89 vs. 34.33 ± 8.91and 53.43 ± 16.14) of gastrointestinal quality of life index were significantly better in study group (P < 0.05).

Improved gastrointestinal functional recovery, reduced postoperative complications, and improved quality of life, all were a result of implementing postoperative enhanced recovery among patients with perforated peptic ulcer.

Trial Registration Number (TRN) -URL: https://www.clinicaltrials.gov. Unique identifier: NCT06570018 Date of registration July August 22, 2024

## Full-text entities

- **Diseases:** postoperative (MESH:D019106), perforated peptic ulcer (MESH:D010439)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC11970008/full.md

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Source: https://tomesphere.com/paper/PMC11970008