# The COVID-19 pandemic and critical laboratory functions. Can fast-track molecular testing reduce work absence in the laboratory?

## TL;DR

A study shows that rapid molecular testing and infection control measures helped reduce workplace absences in a lab during the pandemic.

## Contribution

The study demonstrates how fast-track PCR testing and IPC measures can maintain lab operations during a pandemic.

## Key findings

- Most SARS-CoV-2 infections in the lab were acquired outside the workplace.
- Workplace sickness absence decreased during the pandemic compared to pre-pandemic levels.
- Rapid testing and IPC measures minimized outbreaks and maintained diagnostic operations.

## Abstract

Amid the SARS-CoV-2 pandemic, laboratories faced the challenge of maintaining diagnostic operations while adhering to infection prevention and control (IPC) guidelines. We investigated the impact of implementing rapid molecular testing of employees of a large medical laboratory to prevent workplace transmission.

To evaluate if fast-track PCR diagnostics, alongside local infection control measures, could reduce internal transmission and workplace sickness absence.

Employees with respiratory symptoms, but testing negative for SARS-CoV-2, were allowed to work if clinically healthy. All included employees completed a questionnaire and underwent SARS-CoV-2 antibody testing post-pandemic. Data on sickness absence were retrieved from local human resources systems, and comparative analyses were conducted between the pre-pandemic and pandemic periods.

Of 153 participants, 84 (55%) reported having had COVID-19, with 12 (14%) suspecting workplace transmission. Six (4%) tested positive for SARS-CoV-2 IgG nucleocapsid despite no COVID-19 diagnosis. Among 101 (66%) reporting respiratory symptoms and negative SARS-CoV-2 tests, 80 (79%) were allowed to return to the workplace. Mean workplace sickness absence during the pandemic 2020 (3.74%) and 2021 (4.19%) was significant lower compared with sickness absence in the laboratory before the pandemic in 2019 (4.54%). No larger outbreaks in the laboratory were recorded.

SARS-CoV-2 infections in the laboratory were mostly symptomatic and acquired outside the workplace. The combination of local IPC and rapid and frequent testing of employees facilitated an effective infection control and minimized workplace absence, maintain diagnostic operations.