# Role of Chimeric Antigen Receptor T-Cells in the Evolving Therapeutic Landscape of Multiple Myeloma: A Literature Review

## TL;DR

This paper reviews how CAR-T therapy is becoming a promising treatment for multiple myeloma, focusing on its mechanism, effectiveness, and safety.

## Contribution

The paper provides a comprehensive literature review on the application of CAR-T therapy in multiple myeloma treatment.

## Key findings

- CAR-T therapy shows promising outcomes in multiple myeloma patients who have failed other treatments.
- The review highlights the mechanism, effectiveness, and safety profile of CAR-T therapy in MM.

## Abstract

Multiple myeloma (MM) is a quotidian malignant disorder of plasma cells. It is hallmarked by the uncontrolled growth of bone marrow plasma cells, leading to multiorgan dysfunction. Despite ongoing advancements in remedies, including chemotherapy, radiotherapy, immunomodulatory drugs, stem cell transplantations, and countless other lines of treatment, the management of MM remains a challenge.

Recent studies indicate promising outcomes with chimeric antigen receptor T-cell (CAR-T) therapy, especially in patients who have previously undergone other treatments. This literature review aims to explore various facets of MM and the progress made with CAR-T therapy, emphasizing the mechanism, effectiveness, and safety profile.