# Gastric metastasis from high-grade soft tissue sarcoma: a rare occurrence with literature review

**Authors:** Blagica Krsteska, Tamara Angelovska, Panche Zdravkovski, Xhem Adem, Teodora Todorova, Milan Samardziski, Darko Dzambaz, Slavica Kostadinova-Kunovska

PMC · DOI: 10.1093/jscr/rjaf192 · Journal of Surgical Case Reports · 2025-04-04

## TL;DR

This paper reports a rare case of a high-grade soft tissue sarcoma metastasizing to the stomach four years after initial diagnosis.

## Contribution

The novelty lies in documenting a rare gastric metastasis from fibrosarcoma, highlighting its clinical presentation and management.

## Key findings

- Gastric metastasis from high-grade soft tissue sarcoma occurred 4 years after initial diagnosis.
- Palliative gastric resection was performed due to severe anemia caused by the metastasis.
- Literature review shows metastatic leiomyosarcomas are most commonly reported to metastasize to the stomach.

## Abstract

Metastasis of high-grade soft tissue sarcoma to the stomach is an extremely rare occurrence. While sarcomas can spread to distant organs, they most commonly metastasize to the lungs, liver, and bones. We report a unique case of gastric metastasis from a high-grade soft tissue sarcoma, occurring 4 years after the initial diagnosis of fibrosarcoma in the right femoral region. The patient did not undergo adjuvant chemotherapy and developed a large soft tissue metastasis in the left gluteal region 2 years later. After 4 years, he presented with a second soft tissue metastasis and suspected metastatic lung nodules. Symptoms of melena and severe anemia prompted a gastroscopic examination, which revealed gastric metastasis from a high-grade soft tissue sarcoma. Due to severe anemia, a palliative gastric resection was performed. A review of the literature indicates that metastatic leiomyosarcomas are the most frequently reported sarcoma subtype metastasizing to the stomach.

## Linked entities

- **Diseases:** fibrosarcoma (MONDO:0002676), leukemia (MONDO:0004355), anemia (MONDO:0002280)

## Full-text entities

- **Diseases:** fibrosarcoma (MESH:D005354), anemia (MESH:D000740), melena (MESH:D008551), sarcoma (MESH:D012509), leiomyosarcomas (MESH:D007890), Gastric metastasis (MESH:D009362)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11969146/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11969146/full.md

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Source: https://tomesphere.com/paper/PMC11969146