# Leptomeningeal Seeding of Pituitary Adenoma in a Young Lady With Neglected Gigantism: An Extremely Rare Case Report

**Authors:** Sadegh Bagherzadeh, Milad Shafizadeh, Seyed Mohammad Tavangar, Alireza Khoshnevisan

PMC · DOI: 10.1002/ccr3.70342 · Clinical Case Reports · 2025-04-04

## TL;DR

A rare case of a young woman with a pituitary tumor that spread to the meninges highlights the importance of thorough diagnosis and understanding hormonal health.

## Contribution

Highlights the rare presentation of leptomeningeal seeding in pituitary adenoma and emphasizes the importance of assessing menstrual status in diagnosing hormonal issues.

## Key findings

- Pituitary adenoma can present with leptomeningeal seeding at initial diagnosis.
- Menstrual status assessment is crucial for evaluating hypothalamic–pituitary axis function in low socioeconomic conditions.

## Abstract

Pituitary neuroendocrine tumors can sometimes present with leptomeningeal seeding at their initial diagnosis, emphasizing the need for thorough evaluation in cases of leptomeningeal involvement. Additionally, it is crucial for general physicians to inquire about a patient's menstrual status, particularly in low socioeconomic conditions, as this information can provide valuable insights into the hypothalamic–pituitary axis function.

## Linked entities

- **Diseases:** pituitary adenoma (MONDO:0006373), gigantism (MONDO:0020479)

## Full-text entities

- **Diseases:** Pituitary Adenoma (MESH:D010911), Neglected Gigantism (MESH:D005877), Pituitary neuroendocrine tumors (MESH:D018358)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11969041/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC11969041/full.md

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Source: https://tomesphere.com/paper/PMC11969041