# Editorial: Recent advances in our understanding of NEC pathogenesis, diagnosis, and treatment - volume II

**Authors:** Xiaocai Yan, Minesh Khashu

PMC · DOI: 10.3389/fped.2025.1587284 · Frontiers in Pediatrics · 2025-03-21

## Full-text entities

- **Genes:** TLR4 (toll like receptor 4) [NCBI Gene 7099] {aka ARMD10, CD284, TLR-4, TOLL}, ALPI (alkaline phosphatase, intestinal) [NCBI Gene 248] {aka IAP}
- **Diseases:** inflammatory (MESH:D007249), critically ill (MESH:D016638), neuroinflammation (MESH:D000090862), hypoxia (MESH:D000860), anemia (MESH:D000740), reperfusion injury (MESH:D015427), gut injuries (MESH:C536735), neurodevelopmental delays (MESH:D006968), coagulopathy (MESH:D001778), gastrointestinal emergency (MESH:D005767), short gut syndrome (MESH:C537327), COVID-19 (MESH:D000086382), NEC (MESH:D020345), perforation (MESH:D057112), intestinal injury (MESH:D007410), bloodstream infections (MESH:D018805)
- **Chemicals:** oxygen (MESH:D010100), butyrate (MESH:D002087), LPS (MESH:D008070), short-chain fatty acid (MESH:D005232)
- **Species:** Sus scrofa (pig, species) [taxon 9823], Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC11968342