# Successful Management of a Parapharyngeal Abscess With Pharyngeal Perforation and Internal Jugular Vein Thrombosis in a Patient With a History of Lymphoma

**Authors:** Fernando Dip, Rene Aleman, Federico Marinelli, Alberto Rancati, Diego Sinagra

PMC · DOI: 10.7759/cureus.80031 · Cureus · 2025-03-04

## TL;DR

This paper describes the successful treatment of a rare and severe throat infection in a lymphoma patient requiring surgery and antibiotics.

## Contribution

The paper presents a novel case of a complex parapharyngeal abscess managed with a multidisciplinary surgical and medical approach.

## Key findings

- A multidisciplinary approach including drainage and surgical repair resolved the infection.
- Early recognition and tailored postoperative care were critical for successful recovery.
- The case demonstrates effective management of high-risk complications in DNSIs.

## Abstract

Deep neck space infections (DNSIs) are rare but potentially life-threatening conditions due to their rapid progression and proximity to vital structures. The conventional management of this condition is multidisciplinary, requiring broad-spectrum antibiotic therapy and surgical intervention when deemed necessary. The prognosis of DNSIs relies on the immune status of its host, severity, and anatomical location, with high and fluctuating mortality rates if inadequately managed. A timely intervention prevents the progression to higher-risk complications, including Lemierre syndrome, mediastinitis, and respiratory failure. The authors herein present the case of a complicated parapharyngeal abscess requiring a multidisciplinary medical and surgical approach via abscess drainage, pharyngeal defect repair, and muscle flap reinforcement. This case highlights the importance of early recognition, surgical expertise, and tailored postoperative care in the management of complex DNSIs.

## Linked entities

- **Diseases:** lymphoma (MONDO:0003659)

## Full-text entities

- **Diseases:** Thrombosis (MESH:D013927), respiratory failure (MESH:D012131), mediastinitis (MESH:D008480), Lemierre syndrome (MESH:D057831), Lymphoma (MESH:D008223), DNSIs (MESH:D006258), Parapharyngeal Abscess (MESH:D000038)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC11967753/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11967753/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC11967753/full.md

---
Source: https://tomesphere.com/paper/PMC11967753