# Community-Based Delivery and Administration of SARS-CoV-2 Antigen Rapid Diagnostic Tests: An Operational Research Study in Marketplaces in Malawi and Zambia

**Authors:** Fiona Gambanga, Lindiwe Nchimunya, Joseph Makondesa, Chancy Chavula, Namwaka Mulenga, Tamara Mwenifumbo, Francis Chitanda, Jonathan Mtaula, Yucheng Tsai, Joseph Bitilinyu-Bangoh, Andrews Gunda, Aaron Shibemba, Powell Choonga, Shaukat Khan, Trevor Peter

PMC · DOI: 10.4269/ajtmh.23-0785 · The American Journal of Tropical Medicine and Hygiene · 2024-10-01

## TL;DR

This study shows that community-based testing for COVID-19 using rapid diagnostic tests in marketplaces is feasible and acceptable in Malawi and Zambia.

## Contribution

The study provides evidence on the operational feasibility and acceptability of community-based SARS-CoV-2 antigen testing in marketplaces in two African countries.

## Key findings

- Community-based testing in marketplaces was found to be feasible and acceptable in Malawi and Zambia.
- High acceptability of nasal swab sample collection was reported by participants in both countries.
- The positivity rates for SARS-CoV-2 were 3.3% in Malawi and 0.5% in Zambia.

## Abstract

To expand access to testing beyond public health facilities and to strengthen surveillance efforts for COVID-19, community testing using COVID-19 antigen-based rapid diagnostic tests (Ag-RDTs) was identified as a major area of focus in Malawi and Zambia. This research aimed to gather evidence on the feasibility and acceptability of community testing in marketplaces. A cross-sectional study with a mixed-methods design was conducted in marketplaces in Malawi and Zambia to understand operational considerations for the implementation of Ag-RDTs for SARS-CoV-2 in a community setting. Programmatic data were collected prospectively as individuals were tested from June to September 2022. COVID-19 testing was done using Abbott Panbio nasal swab test kits. Semi-qualitative questionnaires were administered to individuals who tested, healthcare workers, and site-based personnel. Data were collected electronically via the SurveyCTO platform and analyzed using STATA. In Malawi, 2,348 participants were tested, and in Zambia, 1,723 people were tested for COVID-19. In Zambia, participants were 46% female, with a median age of 28 years, whereas in Malawi, participants were 69% female, with a median age of 37 years. In Malawi, 78 positive cases were reported (3.3% positivity rate), and in Zambia 10 positive cases were reported (0.5% positivity rate). In Zambia, 99% of 300 participants and in Malawi, 92% of 1,158 testers found the market testing experience and sample collection acceptable. Community testing is a feasible and acceptable intervention to increase testing access in Malawi and Zambia, especially when coupled with community awareness campaigns and mobilization.

## Linked entities

- **Diseases:** SARS-CoV-2 (MONDO:0100096), COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382)
- **Chemicals:** Ag (MESH:D012834)
- **Species:** Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11965721/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC11965721/full.md

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Source: https://tomesphere.com/paper/PMC11965721