# The Cognitive Profile in Adolescents With Anorexia Nervosa and the Relationship With Autism and ADHD: A Pilot Study

**Authors:** Sandra Rydberg Dobrescu, Karin Dahlin, Louise Karjalainen, Annelie Bördal Montonen, Helena Klint, Ingrid Stenberg, Gunilla Paulson Karlsson, Elisabet Wentz

PMC · DOI: 10.1002/erv.3168 · European Eating Disorders Review · 2024-12-28

## TL;DR

This pilot study explores cognitive abilities in adolescents with anorexia nervosa and how they relate to autism and ADHD traits, finding limited evidence of cognitive differences after weight recovery.

## Contribution

The study is novel in examining cognitive profiles and their relation to autism and ADHD traits in adolescents with anorexia nervosa, including parent-child cognitive similarities.

## Key findings

- Weight-restored adolescents with anorexia nervosa scored higher on the Group Embedded Figures Test than healthy peers.
- A moderate correlation was found between fathers and children in the object assembly subtest.
- ASD and ADHD traits were common in the anorexia nervosa group and not solely due to starvation.

## Abstract

We aimed to examine the cognitive profile in adolescents with anorexia nervosa (AN) and its association with traits of autism spectrum disorder (ASD) and ADHD. In addition, resemblance in the cognitive profile between youths with AN and their parents was explored.

Adolescent females with acute AN (n = 20) and a healthy comparison group (n = 28) completed neuropsychological tasks of set‐shifting (Trail making test, Wisconsin Card Sorting Test) and central coherence (Rey Complex Figures Task, Group Embedded Figures Test, object assembly subtest). In the AN group, mothers and fathers (n = 31) also completed the neuropsychological tasks. Traits of ASD and ADHD were assessed. The AN group was reassessed after weight gain.

Weight‐restored AN adolescents scored higher on the Group Embedded Figures Test than a comparison group (p < 0.001). No other set‐shifting and central coherence differences were found across groups. A father‐child correlation emerged in the object assembly subtest (r = 0.53, p = 0.035). ASD and ADHD traits were common in the AN group and not only related to starvation. No associations were found between neuropsychological deficits and traits of ASD and ADHD.

Scant support was found for weaker central coherence in weight‐recovered adolescents with AN. Set‐shifting impairments could not be observed in young females with acute AN or after weight recovery.

## Linked entities

- **Diseases:** anorexia nervosa (MONDO:0005351), autism spectrum disorder (MONDO:0005258), ADHD (MONDO:0007743)

## Full-text entities

- **Diseases:** neuropsychological deficits (MESH:D009461), ADHD (MESH:D001289), weight gain (MESH:D015430), AN (MESH:D000856), ASD (MESH:D000067877), starvation (MESH:D013217), Autism (MESH:D001321)

## Full text

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## Figures

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## References

68 references — full list in the complete paper: https://tomesphere.com/paper/PMC11965542/full.md

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Source: https://tomesphere.com/paper/PMC11965542