# Chronic Viral Infections and Al Amyloidosis: An Uncommon Association

## TL;DR

This paper reports a rare case of AL amyloidosis linked to HIV, suggesting immune dysregulation may play a role in its development.

## Contribution

The paper highlights a novel association between HIV and AL amyloidosis, suggesting a potential pathogenic link.

## Key findings

- A case of AL amyloidosis was found to be associated with HIV infection.
- The study suggests that HIV-related immune dysregulation may contribute to plasma cell dyscrasias leading to AL amyloidosis.

## Abstract

AL‐amyloidosis is caused by deposition of pathological insoluble proteins in organs and tissues. HIV infection is a multi‐system disorder causing chronic inflammation. We report a case of AL‐amyloidosis associated with HIV suggesting that HIV‐associated immune dysregulation might be critical for pathogenesis of plasma cells dyscrasias and then AL amyloidosis.