# Collagen Membrane: A Viable Option for Oral Soft Tissue Defects—A Case Series

**Authors:** Niroj Khanal, Bibek Kattel, Mehul Rajesh Jaisani, Siddhartha Rai

PMC · DOI: 10.1002/ccr3.70349 · Clinical Case Reports · 2025-04-02

## TL;DR

This paper presents collagen membranes as a promising solution for repairing soft tissue defects after removing oral lesions.

## Contribution

The study introduces collagen sheets as a viable alternative for reconstructing oral soft tissue defects.

## Key findings

- Collagen membranes effectively conceal mucosal defects after surgical removal of dysplastic lesions.
- The use of collagen sheets offers a practical reconstruction option in oral surgery cases.

## Abstract

Timely intervention during the predysplastic or dysplastic stages of red and white lesions is crucial for preventing their progression to oral carcinoma. Following surgical removal, a soft tissue deficit area is created. Surgical excision of these lesions often leads to a mucosal defect. These residual defects can be concealed with skin grafts, mucosal grafts, or xenografts. In this paper, we describe collagen sheets as an excellent reconstruction option, particularly after the loss of soft tissue due to resection of red and white lesions with histologically verified dysplastic features.

## Linked entities

- **Diseases:** oral carcinoma (MONDO:0023644)

## Full-text entities

- **Diseases:** mucosal defect (MESH:D052016), dysplastic (MESH:D004416), oral carcinoma (MESH:D009062), Soft Tissue Defects (MESH:D017695), lesions (MESH:D009059)

## Full text

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## Figures

19 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11964851/full.md

## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC11964851/full.md

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Source: https://tomesphere.com/paper/PMC11964851