# Epidermoid cyst of the penis: A case report

## TL;DR

A rare case of a benign epidermoid cyst on the penis is reported, emphasizing the importance of accurate diagnosis and surgical treatment.

## Contribution

This paper presents a rare clinical case of a penile epidermoid cyst, highlighting diagnostic and treatment approaches.

## Key findings

- Epidermoid cysts on the penis are rare but benign and can be effectively treated with surgical excision.
- Histopathological examination is crucial to confirm the diagnosis and differentiate from malignancies.
- The patient showed no recurrence at the 6-month follow-up after adequate surgical treatment.

## Abstract

Epidermoid cysts are benign, keratin-filled lesions that rarely occur in the genital region. Diagnosis is primarily clinical, but histopathological examination is essential for confirmation. This case highlights a rare occurrence of an epidermoid cyst on the penis, emphasizing clinical features, diagnostic approach, and treatment outcomes.

A 35-year-old male presented with a non-tender, firm, well-circumscribed lesion measuring 2.5 cm × 1.8 cm located on the middle third of the left lateral aspect of the penis. Over eight months, the mass grew, causing pruritus, sexual discomfort, and self-image concerns, without pain or infection. Histopathological analysis confirmed the diagnosis of an epidermoid cyst, with stratified squamous epithelium and keratin-filled cystic spaces.

Although rare in the genital area, epidermoid cysts must be considered in the differential diagnosis of penile lesions. Clinical presentation, including a well-defined, mobile mass, is suggestive of the condition. Histopathological features, such as a cyst lined with squamous epithelium and keratin, are key to distinguishing it from other conditions like squamous cell carcinoma. Surgical excision with a margin is the treatment of choice, and recurrence is uncommon when performed adequately.

Epidermoid cysts of the penis are benign lesions with a favorable prognosis following surgical excision. This case demonstrates the importance of accurate diagnosis and management to avoid misdiagnosis and ensure successful treatment outcomes. The patient showed no recurrence at the 6-month follow-up.

•Rare but benign; requires thorough differential diagnosis•Surgical excision is curative in most cases.•Postoperative surveillance is crucial to avoid recurrence.•Histopathological confirmation is essential to ensure accurate diagnosis and exclude malignancies.

Rare but benign; requires thorough differential diagnosis

Surgical excision is curative in most cases.

Postoperative surveillance is crucial to avoid recurrence.

Histopathological confirmation is essential to ensure accurate diagnosis and exclude malignancies.