# A Rare Case of Endometrial Adenosarcoma and Its Management: A Case Report and Literature Review

**Authors:** Shereen Rafiq, Sofia Ali, Hend Makky Abouzied, Yusra Qamar

PMC · DOI: 10.7759/cureus.79970 · Cureus · 2025-03-03

## TL;DR

This paper reports a rare case of endometrial adenosarcoma in a 52-year-old woman and discusses its diagnosis, treatment, and management challenges.

## Contribution

The novelty lies in presenting a real-world case and literature review to guide clinical management of this rare uterine cancer.

## Key findings

- Endometrial adenosarcoma was diagnosed through histopathological examination after hysterectomy.
- The patient received adjuvant chemotherapy due to the high risk of recurrence.
- Close follow-up is emphasized as critical for managing this rare tumor.

## Abstract

Endometrial adenosarcoma is a rare and aggressive uterine malignancy composed of both epithelial and stromal components, most commonly affecting postmenopausal women. This case report describes the diagnosis of endometrial adenosarcoma in a 52-year-old woman who presented with abnormal vaginal bleeding. A hysterectomy was performed, and a histopathological examination confirmed the diagnosis. Due to the high risk of recurrence, the patient underwent surgical resection followed by adjuvant chemotherapy. Given the rarity of this tumor, its management presents a significant clinical challenge. This case underscores the diagnostic approach, therapeutic strategies, and the critical role of close follow-up in managing endometrial adenosarcoma.

## Full-text entities

- **Diseases:** tumor (MESH:D009369), vaginal bleeding (MESH:D014592), Endometrial Adenosarcoma (MESH:D018195)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11964285/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC11964285/full.md

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Source: https://tomesphere.com/paper/PMC11964285