# Langerhans cell histiocytosis in an adult patient with upper jaw and pulmonary involvement: A case report

## TL;DR

This case report describes a rare instance of Langerhans cell histiocytosis in an adult, affecting the jaw and lungs, and highlights the importance of early diagnosis.

## Contribution

The report presents a rare case of adult-onset LCH with oral and pulmonary involvement, emphasizing the need for dental awareness.

## Key findings

- A 27-year-old man presented with progressive tooth mobility and loss due to LCH.
- Pulmonary involvement was detected via high-resolution computed tomography.
- Systemic chemotherapy led to favorable outcomes in the patient.

## Abstract

Langerhans cell histiocytosis (LCH) is characterized by proliferative histiocyte-like cells. LCH lesions exhibit diverse and nonspecific clinical features, often leading to misdiagnosis and delayed treatment. Primary LCH lesions in the oral cavity remain rare. We report a case of a 27-year-old man with rare adult-onset LCH presenting with progressive mobility of the posterior teeth. The patient experienced increasing tooth mobility and subsequent loss in the upper and lower jaw despite undergoing periodontal treatment. A biopsy of oral mucosal tissue confirmed the Langerhans cell origin. High-resolution computed tomography imaging revealed pulmonary involvement. After undergoing systemic chemotherapy with prednisolone, vinblastine, and etoposide, the patient exhibited favourable follow-up outcomes. This case underscores the value of early diagnosis to prevent disease progression and highlights the need for dentists to be aware of LCH.