# Evaluation of Serum Vitamin D and C Concentrations in Cats With Gingivostomatitis

**Authors:** Farzin Abbasi, Reza Azargoun, Siamak Asri‐Rezaei

PMC · DOI: 10.1002/vms3.70279 · Veterinary Medicine and Science · 2025-04-02

## TL;DR

This study found that cats with gingivostomatitis have lower vitamin D levels compared to healthy cats, but vitamin C levels were similar.

## Contribution

The study identifies a potential link between vitamin D deficiency and feline gingivostomatitis.

## Key findings

- Cats with gingivostomatitis had significantly lower serum vitamin D levels than healthy cats.
- No significant difference in serum vitamin C levels was observed between the two groups.
- The study suggests a possible predisposition to vitamin D deficiency in cats with gingivostomatitis.

## Abstract

To investigate serum vitamin C and D concentrations of cats suffering from gingivostomatitis.

Serum concentrations of vitamins C and D were evaluated in 30 cats of various breeds, including 15 healthy cats and 15 with gingivostomatitis.

Serum vitamin D concentration in the healthy cats (35.36 ± 15.39 ng/mL) was significantly higher than that of the cats with gingivostomatitis (17.54 ± 10.50 ng/mL) (p < 0.05). There was no difference in serum vitamin C concentration between the healthy cats (3.7 ± 0.74 mg/100 mL) and those with gingivostomatitis (3.1 ± 0.72 mg/100 mL) (p < 0.05).

The results of this study suggest that cats with gingivostomatitis are predisposed to vitamin D deficiency. Further studies are required to confirm this finding in a larger study sample and to investigate the potential utility of vitamin D supplementation.

This study investigated the levels of vitamins C and D in the serum of cats suffering from gingivostomatitis. Levels of vitamin D were significantly lower in the patient cats when compared to the healthy cats. No significant difference was observed in the levels of vitamin C between the two groups.

## Linked entities

- **Chemicals:** vitamin C (PubChem CID 54670067)

## Full-text entities

- **Diseases:** Gingivostomatitis (MESH:D013283), vitamin D deficiency (MESH:D014808)
- **Chemicals:** vitamin D (MESH:D014807), Vitamin D and C (-), vitamin C (MESH:D001205)
- **Species:** Felis catus (cat, species) [taxon 9685]

## Full text

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## Figures

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## References

41 references — full list in the complete paper: https://tomesphere.com/paper/PMC11964153/full.md

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Source: https://tomesphere.com/paper/PMC11964153