# Metastatic Parathyroid Carcinoma in a Young Adult With Recurrent Hypercalcemia and Acute Necrotizing Pancreatitis

**Authors:** Moemen Hasaballah, Mohamed Abdulmajeed, Amira Abohegazy

PMC · DOI: 10.7759/cureus.79942 · Cureus · 2025-03-03

## TL;DR

This paper reports a rare case of metastatic parathyroid cancer in a young man with severe hypercalcemia and pancreatitis.

## Contribution

The novelty lies in presenting a rare case of metastatic parathyroid carcinoma with acute necrotizing pancreatitis in a young adult.

## Key findings

- Metastatic parathyroid carcinoma can present with severe hypercalcemia and acute necrotizing pancreatitis.
- The case highlights the diagnostic and management challenges of this rare and aggressive cancer.

## Abstract

Parathyroid carcinoma (PC) is an extremely rare form of endocrine cancer, accounting for a very small proportion of primary hyperparathyroidism cases. Even more extraordinary is metastatic PC presenting with complications such as severe hypercalcemia and pancreatitis. In this report, we present the case of a 33-year-old male patient who developed metastatic PC with recurrent hypercalcemia and acute necrotizing pancreatitis. This case sheds light on the complexities of diagnosing and managing this rare and aggressive condition.

## Linked entities

- **Diseases:** parathyroid carcinoma (MONDO:0012004), hyperparathyroidism (MONDO:0001741), hypercalcemia (MONDO:0001566), pancreatitis (MONDO:0004982)

## Full-text entities

- **Diseases:** Acute Necrotizing Pancreatitis (MESH:D019283), Hypercalcemia (MESH:D006934), endocrine cancer (MESH:D004701), primary hyperparathyroidism (MESH:D049950), pancreatitis (MESH:D010195), PC (MESH:D010282)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11962671/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC11962671/full.md

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Source: https://tomesphere.com/paper/PMC11962671