# Hepatocellular Carcinoma with Vascular and Cardiac Involvement in a Young Patient with Non-Cirrhotic Hepatitis B: A Case Report

## TL;DR

A young man with non-cirrhotic hepatitis B developed advanced liver cancer that spread to his heart, highlighting the need for early HBV detection.

## Contribution

Reports a rare case of HCC with cardiac involvement in a young, non-cirrhotic HBV patient.

## Key findings

- HCC with vascular invasion reached the right heart chambers in a 25-year-old patient.
- The patient had undiagnosed non-cirrhotic HBV, which likely contributed to HCC development.
- Despite treatment, the prognosis for advanced HCC with cardiac involvement remains poor.

## Abstract

Hepatocellular carcinoma (HCC) is a highly vascular malignancy with the potential for intravascular invasion. However, vascular extension into the cardiac chambers is extremely rare.

We present a 25-year-old male patient in whom the investigation of a cardiac murmur led to the discovery of an intracardiac mass that proved to be advanced-stage HCC with vascular invasion of the right heart. The patient had a previously unknown non-cirrhotic chronic hepatitis B virus (HBV) infection. Despite antiviral therapy and systemic treatment for HCC, he eventually died about 1 month later due to disease progression.

This report highlights the importance of early HBV diagnosis and treatment for timely detection and management of HCC. Advanced-stage HCC, particularly with cardiac involvement, has an extremely poor prognosis.