Oral verruciform xanthoma (OVX) of lower labial mucosa, presenting as a plaque in tobacco users: an unusual case report with literature review

TL;DR

This case report describes a rare oral lesion resembling a white plaque in a tobacco user, diagnosed as oral verruciform xanthoma.

Contribution

The novelty lies in presenting an unusual case of OVX in the lower labial mucosa with a focus on clinical and histopathological features.

Findings

The lesion was diagnosed as oral verruciform xanthoma despite its plaque-like appearance.

Histopathological and immunohistochemical features confirmed the diagnosis of OVX.

Tobacco use was identified as a potential contributing factor in this case.

Abstract

Oral verruciform xanthoma (OVX) is an uncommon lesion known for its wart-like appearance, primarily affecting the oral mucosa. This case report delves into a distinctive presentation of OVX, a rare benign lesion typically characterised by its manifestation as a white plaque in the oral cavity. Clinical features, histological findings, pathogenesis and their implications in the context of differential diagnosis has been discussed. The patient had a history of regular tobacco use, and despite initially presenting as a white plaque, the histopathological and immunohistochemical features strongly suggested verruciform xanthoma.

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