# Case Report: Rheumatoid arthritis patient with hip joint infection and acetabular protrusion undergoing total hip arthroplasty: a case study and literature review

**Authors:** Jun Zhou, Weijie Zhou, Peng Wang, Yinwei Zhang, Weitao Chu, Jun Fan, Hui Lu

PMC · DOI: 10.3389/fsurg.2025.1534279 · 2025-03-18

## TL;DR

A rheumatoid arthritis patient with a hip joint infection and deformity underwent hip replacement surgery and recovered after antibiotic treatment.

## Contribution

Highlights the importance of early infection detection in RA patients with hip complications.

## Key findings

- Gram-negative rod bacteria were identified in synovial fluid during surgery.
- Aggressive postoperative anti-infective therapy controlled the infection effectively.
- Early diagnosis and treatment are crucial for managing infections in RA patients with hip deformities.

## Abstract

The chronic autoimmune disease rheumatoid arthritis (RA) affects primarily the synovial joints, leading to hip joint deformity and dysfunction manifestations such as acetabular protrusion and joint infection. We present the case of a female patient RA complicated by severe hip arthritis and acetabular protrusion syndrome. The disease progressed rapidly with elevated preoperative inflammatory markers, initially overlooking hip joint infection. The patient underwent total hip arthroplasty, and intraoperative synovial fluid bacterial culture revealed Gram-negative rod bacteria. Aggressive postoperative anti-infective therapy effectively controlled the infection. Therefore, early diagnosis and treatment of infections are particularly important.

## Linked entities

- **Diseases:** rheumatoid arthritis (MONDO:0008383)

## Full-text entities

- **Diseases:** hip joint deformity and dysfunction (MESH:D007592), autoimmune disease (MESH:D001327), hip joint infection (MESH:D007239), hip arthritis (MESH:D001168), inflammatory (MESH:D007249), acetabular protrusion (OMIM:142700), RA (MESH:D001172)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11958972/full.md

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Source: https://tomesphere.com/paper/PMC11958972