# 928 Epidural Anesthesia for Pain Relief in Patients with Severe Burns

**Authors:** Max Silverstein, Ujalashah Dhanani, Pandora Chua, Clifford Sheckter, Yvonne Karanas

PMC · DOI: 10.1093/jbcr/iraf019.459 · 2025-04-01

## TL;DR

Epidural anesthesia reduces pain and opioid use in burn patients, offering a safe alternative for pain management.

## Contribution

This study demonstrates the effectiveness of epidural anesthesia in managing burn pain and reducing opioid consumption.

## Key findings

- Epidural anesthesia significantly reduced opioid consumption from 92.5 to 58.1 MME/day.
- Average pain scores dropped from 6.25 to 2.45 after epidural placement.
- No major complications were observed in patients receiving epidural anesthesia.

## Abstract

Patients with severe burns endure intense pain, which is amplified by serial operations, daily dressing changes, and regular physical/occupational therapy. Inadequate pain control causes secondary psychological trauma and opioid dependence. Regional anesthesia techniques are effective for managing pain in a variety of clinical scenarios, including severe burns. While peripheral nerve blocks have become increasingly popular in the management of isolated burns to the extremities, there have been few reports on the use of neuraxial anesthesia to treat burn pain. Here, we describe the inclusion of epidural anesthesia in our algorithm for management of burns to the lower trunk, bilateral lower extremities, buttocks, and perineum. We hypothesized that epidural anesthesia would be associated with reduced opioid use and improved pain scores.

We performed a retrospective review of all patients admitted to a verified burn center who underwent epidural catheter placement between 2018 and 2024. Visual analog scale (VAS) pain scores and opioid consumption (standardized in morphine milligram equivalents [MME]) were extracted for the several days before and after placement of each patient’s first epidural catheter. Statistical testing was performed with the Wilcoxon Rank Sum Test (significance at p ≤ 0.05).

11 patients underwent epidural catheterization in our burn unit. Of those patients, 4 were male and 7 were female, with a mean age of 54.8 (SD 22.0, range 12 – 88) years. An average of 1.8 (SD 1.3) catheters were placed per patient, for a total of 20 catheters. Epidural catheters were removed 4.0 (SD 1.9, range 1 – 8) days after placement. All patients experienced significant reductions in daily opioid consumption (92.5 MME/day pre-epidural to 58.1 MME/day post-epidural, p = 0.008) and average pain scores (6.25 pre-epidural to 2.45 post-epidural; p = 0.008). Minor complications including nausea/vomiting and pruritis occurred in 4 patients. There were no major complications or infections.

Epidural anesthesia is safe and effective for relieving pain and decreasing opioid consumption in burn patients.

Burn centers should consider neuraxial anesthesia for pain management in appropriate patients. These techniques require close collaboration between surgeons and regional anesthesiologists.

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## Linked entities

- **Diseases:** burns (MONDO:0043519)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC11958581/full.md

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Source: https://tomesphere.com/paper/PMC11958581